ホルモノネチン

ホルモノネチン
	IUPAC名 7-hydroxy-3-(4-methoxyphenyl)chromen-4-one
	別称 Biochanin B; Formononetol; 7-Hydroxy-4'-methoxyisoflavone; 4'-O-methyldaidzein
識別情報
CAS登録番号	485-72-3
PubChem	5280378
ChemSpider	4444070
日化辞番号	J12.525C
KEGG	C00858
ChEBI	CHEBI:18088 ;
ChEMBL	CHEMBL242341
バイルシュタイン	237979
	SMILES O=C\1c3c(O/C=C/1c2ccc(OC)cc2)cc(O)cc3;
	InChI InChI=1S/C16H12O4/c1-19-12-5-2-10(3-6-12)14-9-20-15-8-11(17)4-7-13(15)16(14)18/h2-9,17H,1H3 Key: HKQYGTCOTHHOMP-UHFFFAOYSA-N ; InChI=1/C16H12O4/c1-19-12-5-2-10(3-6-12)14-9-20-15-8-11(17)4-7-13(15)16(14)18/h2-9,17H,1H3 Key: HKQYGTCOTHHOMP-UHFFFAOYAJ;
特性
化学式	C16H12O4
モル質量	268.26 g/mol
	特記なき場合、データは常温 (25 °C)・常圧 (100 kPa) におけるものである。

ホルモノネチン(英: Formononetin)はイソフラボンの一種。ダイゼインの4'位がO-メチル化された化合物。

存在

Medjakovic, S.; Jungbauer, A. (2008). “Red Clover Isoflavones Biochanin A and Formononetin are Potent Ligands of the Human Aryl Hydrocarbon Receptor”. The Journal of Steroid Biochemistry and Molecular Biology 108 (1–2): 171–177. doi:10.1016/j.jsbmb.2007.10.001. PMID 18060767.
Fedoreyev, S.A; Pokushalova, T.V; Veselova, M.V; Glebko, L.I; Kulesh, N.I; Muzarok, T.I; Seletskaya, L.D; Bulgakov, V.P et al. (2000). “Isoflavonoid production by callus cultures of Maackia amurensis”. Fitoterapia 71 (4): 365. doi:10.1016/S0367-326X(00)00129-5. PMID 10925005.
Li, Shang; Dang, Yuanye; Zhou, Xuelin; Huang, Bin; Huang, Xiaohui; Zhang, Zherui; Kwan, Yiu Wa; Chan, Shun Wan et al. (2015). “Formononetin promotes angiogenesis through the estrogen receptor alpha-enhanced ROCK pathway”. Scientific Reports 5. doi:10.1038/srep16815.
You-Ping Zhu. Chinese Materia Medica: Chemistry, Pharmacology and Applications. p. 622. ISBN 9057022850

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