リンゴ酸デヒドロゲナーゼ (NADP+)
リンゴ酸デヒドロゲナーゼ (NADP+)（malate dehydrogenase (NADP+)）は、次の化学反応を触媒する酸化還元酵素である。
- (S)-リンゴ酸 + NADP+ オキサロ酢酸 + NADPH + H+
| リンゴ酸デヒドロゲナーゼ (NADP+) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| 識別子 | |||||||||
| EC番号 | 1.1.1.82 | ||||||||
| CAS登録番号 | 37250-19-4 | ||||||||
| データベース | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB構造 | RCSB PDB PDBj PDBe PDBsum | ||||||||
| 遺伝子オントロジー | AmiGO / QuickGO | ||||||||
| |||||||||
反応式の通り、この酵素の基質は(S)-リンゴ酸とNADP+、生成物はオキサロ酢酸とNADPHとH+である。
組織名は(S)-malate:NADP+ oxidoreductaseで、別名にNADP+-malic enzyme, NADP+-malate dehydrogenase, malic dehydrogenase (nicotinamide adenine dinucleotide phosphate), malate NADP+ dehydrogenase, NADP+ malate dehydrogenase, NADP+-linked malate dehydrogenase, malate dehydrogenase (NADP+)がある。
参考文献
- Connelly JL, Danner DJ, Bowden JA (1968). “Branched chain alpha-keto acid metabolism. I. Isolation, purification, and partial characterization of bovine liver alpha-ketoisocaproic:alpha-keto-beta-methylvaleric acid dehydrogenase”. J. Biol. Chem. 243: 1198–203. PMID 5689906.
- Johnson HS (1971). “NADP-malate dehydrogenase: photoactivation in leaves of plants with Calvin cycle photosynthesis”. Biochem. Biophys. Res. Commun. 43: 703–9. doi:10.1016/0006-291X(71)90672-3. PMID 4397919.
- Johnson HS, Hatch MD (1970). “Properties and regulation of leaf nicotinamide-adenine dinucleotide phosphate-malate dehydrogenase and 'malic' enzyme in plants with the C4-dicarboxylic acid pathway of photosynthesis”. Biochem. J. 119: 273–80. PMID 4395182.
関連項目
- リンゴ酸デヒドロゲナーゼ（NAD+型）
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