3-オキソアシル(アシル輸送タンパク質)レダクターゼ
3-オキソアシル[アシル輸送タンパク質]レダクターゼ（3-oxoacyl-[acyl-carrier-protein] reductase）は、次の化学反応を触媒する酸化還元酵素である。
- (3R)-3-ヒドロキシアシル-[アシル輸送タンパク質] + NADP+ 3-オキソアシル-[アシル輸送タンパク質] + NADPH + H+
| 3-オキソアシル[アシル輸送タンパク質]レダクターゼ | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| 識別子 | |||||||||
| EC番号 | 1.1.1.100 | ||||||||
| CAS登録番号 | 37250-34-3 | ||||||||
| データベース | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB構造 | RCSB PDB PDBj PDBe PDBsum | ||||||||
| 遺伝子オントロジー | AmiGO / QuickGO | ||||||||
| |||||||||
すなわち、この酵素の基質は(3R)-3-ヒドロキシアシル-[アシル輸送タンパク質]とNADP+、生成物は3-オキソアシル-[アシル輸送タンパク質]とNADPHとH+である。
組織名は(3R)-3-hydroxyacyl-[acyl-carrier protein]:NADP+ oxidoreductaseで、別名にβ-ketoacyl-[acyl-carrier protein](ACP) reductase, beta-ketoacyl acyl carrier protein (ACP) reductase, β-ketoacyl reductase, β-ketoacyl thioester reductase, β-ketoacyl-ACP reductase, β-ketoacyl-acyl carrier protein reductase, 3-ketoacyl acyl carrier protein reductase, NADPH-specific 3-oxoacyl-[acylcarrier protein]reductase, 3-oxoacyl-[ACP]reductase, (3R)-3-hydroxyacyl-[acyl-carrier-protein]:NADP+ oxidoreductaseがある。
参考文献
- Prescott DJ, Vagelos PR (1972). “Acyl carrier protein”. Adv. Enzymol. Relat. Areas. Mol. Biol. 36: 269–311. PMID 4561013.
- Shimakata T, Stumpf PK (1982). “Purification and characterizations of beta-Ketoacyl-[acyl-carrier-protein] reductase, beta-hydroxyacyl-[acylcarrier-protein] dehydrase, and enoyl-[acyl-carrier-protein] reductase from Spinacia oleracea leaves”. Arch. Biochem. Biophys. 218: 77–91. PMID 6756317.
- Toomey RE, Wakil SJ (1966). “Studies on the mechanism of fatty acid synthesis. XV. Preparation and general properties of beta-ketoacyl acyl carrier protein reductase from Escherichia coli”. Biochim. Biophys. Acta. 116: 189–97. PMID 4381013.
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